Genes in Space is a unique program aimed at inspiring young minds to tackle real-world challenges in the biological and physical sciences. Established in 2015 through a collaboration between Boeing and miniPCR bio, with additional support from the ISS National Laboratory and New England Biolabs, the program encourages creativity, collaboration, and critical thinking among students. Participants are tasked with designing DNA experiments that address various challenges in space exploration, such as detecting alien life, understanding the impact of space travel on human organs, and exploring bioengineering possibilities for colonizing new worlds. The program primarily serves students in grades 7 through 12, providing a hands-on learning experience with biotechnology tools like PCR and gel electrophoresis. Workshops are offered to middle and high school teachers, enabling them to bring the latest in biology and space exploration into their classrooms. These workshops are free and come with lesson plans, worksheets, and educational videos. Additionally, participants gain access to biotechnology equipment loans, making the program accessible and practical. Genes in Space is delivered through a combination of in-person workshops and hands-on projects, culminating in the opportunity for students to see their experiments launched to the International Space Station. The main outcomes and benefits of participating include gaining practical skills in biotechnology, understanding the scientific method, and contributing to meaningful scientific research that could have real-world applications in space exploration.