"Genome Engineering" is a pre-college online course provided by Rice University that gives participants a deep understanding of genome engineering and its role in treating diseases. The course focuses on the human genome, its genetic makeup, and how it can be edited to treat hereditary disorders such as sickle cell disease. It also covers the ethical aspects of genome engineering and the comparison of various design tools used in the medical field. The curriculum includes studying DNA and RNA biomolecules, describing genetic variations in the human genome, and understanding how changes in a single nucleotide can produce sickle cell disease. Participants will also learn the essentials of genome editing and its advantages over traditional medication, and understand the working of the CRISPR/Cas9 system. The course is delivered entirely online, providing students the flexibility to study anywhere, anytime at their own pace. It is one of the multi-length courses offered by Rice University throughout the year. The course is supported by mentors who are well-versed in the subject matter and provide guidance, encouragement, and feedback on assignments. Students who are 13 years old and above are eligible to apply for this course. It is an excellent starting point for those considering a college major or career in this field. Upon completion of the course, participants will gain a comprehensive understanding of genome engineering and its applications in the medical field.